1NKM
Complex structure of HCMV Protease and a peptidomimetic inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Assemblin | polymer | 256 | 28130.5 | 2 | UniProt (P16753) Pfam (PF00716) | Human herpesvirus 5 (Human cytomegalovirus) | Protease, Capsid assembly protein |
| 2 | C (A) | N-(6-aminohexanoyl)-3-methyl-L-valyl-3-methyl-L-valyl-N~1~-[(2S,3S)-3-hydroxy-4-oxo-4-{[(1R)-1-phenylpropyl]amino}butan-2-yl]-N~4~,N~4~-dimethyl-L-aspartamide | non-polymer | 717.9 | 1 | BIRD (PRD_000283) Chemie (0FP) |
Sequence modifications
A, B: 1 - 256 (UniProt: P16753)
| PDB | External Database | Details |
|---|---|---|
| Gln 143 | Ala 143 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 56261.1 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 717.9 | |
| All* | Total formula weight | 56979.0 |
