1NF7
Ternary complex of the human type II Inosine Monophosphate Dedhydrogenase with Ribavirin Monophosphate and C2-Mycophenolic Adenine Dinucleotide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Inosine-5'-monophosphate dehydrogenase 2 | polymer | 514 | 55874.9 | 2 | UniProt (P12268) Pfam (PF00478) Pfam (PF00571) In PDB | Homo sapiens (human) | IMP dehydrogenase 2, IMPDH-II, IMPD 2 |
| 2 | A, B | POTASSIUM ION | non-polymer | 39.1 | 2 | Chemie (K) | |||
| 3 | A, B | RIBAVIRIN MONOPHOSPHATE | non-polymer | 324.2 | 2 | Chemie (RVP) | |||
| 4 | A, B | {[5-(6-AMINO-PURIN-7-YL)-3,4-DIHYDROXY-TETRAHYDRO-FURAN-2-YLMETHOXY]-HYDROXY-PHOSPHORYLMETHYL}-PHOSPHONIC ACID MONO-[2-(4-HYDROXY-6-METHOXY-7-METHYL-3-OXO-1,3-DIHYDRO-ISOBENZOFURAN-5-YL)-ETHYL] ESTER | non-polymer | 645.5 | 2 | Chemie (MYD) | |||
| 5 | B | UNKNOWN | non-polymer | 103.1 | 11 | Chemie (UNK) | |||
| 6 | water | water | 18.0 | 93 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 111749.7 | |
| Non-Polymers* | Number of molecules | 17 |
| Total formula weight | 3151.8 | |
| All* | Total formula weight | 114901.5 |
