1NF7
Ternary complex of the human type II Inosine Monophosphate Dedhydrogenase with Ribavirin Monophosphate and C2-Mycophenolic Adenine Dinucleotide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Inosine-5'-monophosphate dehydrogenase 2 | polymer | 514 | 55874.9 | 2 | UniProt (P12268) Pfam (PF00478) Pfam (PF00571) | Homo sapiens (human) | IMP dehydrogenase 2, IMPDH-II, IMPD 2 |
| 2 | C, F (A, B) | POTASSIUM ION | non-polymer | 39.1 | 2 | Chemie (K) PubChem (813) | |||
| 3 | D, G (A, B) | RIBAVIRIN MONOPHOSPHATE | non-polymer | 324.2 | 2 | Chemie (RVP) PubChem (29986967) PubChem (59034322) PubChem (59895799) PubChem (45040365) PubChem (91345184) PubChem (59892659) PubChem (70536421) PubChem (90788486) PubChem (92145095) PubChem (92261915) PubChem (92261916) PubChem (92261917) PubChem (100252) PubChem (321727) PubChem (5748447) PubChem (146830266) PubChem (172677295) | |||
| 4 | E, H (A, B) | {[5-(6-AMINO-PURIN-7-YL)-3,4-DIHYDROXY-TETRAHYDRO-FURAN-2-YLMETHOXY]-HYDROXY-PHOSPHORYLMETHYL}-PHOSPHONIC ACID MONO-[2-(4-HYDROXY-6-METHOXY-7-METHYL-3-OXO-1,3-DIHYDRO-ISOBENZOFURAN-5-YL)-ETHYL] ESTER | non-polymer | 645.5 | 2 | Chemie (MYD) PubChem (44375518) PubChem (60132723) PubChem (3011791) PubChem (10304926) PubChem (477579) PubChem (142147527) | |||
| 5 | I, J, K, L, M... (B) | UNKNOWN LIGAND | non-polymer | 103.1 | 11 | Chemie (UNL) | |||
| 6 | T, U (A, B) | water | water | 18.0 | 93 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 111749.7 | |
| Non-Polymers* | Number of molecules | 17 |
| Total formula weight | 3151.8 | |
| All* | Total formula weight | 114901.5 |
