1NF7

Ternary complex of the human type II Inosine Monophosphate Dedhydrogenase with Ribavirin Monophosphate and C2-Mycophenolic Adenine Dinucleotide

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Inosine-5'-monophosphate dehydrogenase 2	polymer	514	55874.9	2	UniProt (P12268) Pfam (PF00478) Pfam (PF00571)	Homo sapiens (human)	IMP dehydrogenase 2, IMPDH-II, IMPD 2
2	C, F (A, B)	POTASSIUM ION	non-polymer		39.1	2	Chemie (K)
3	D, G (A, B)	RIBAVIRIN MONOPHOSPHATE	non-polymer		324.2	2	Chemie (RVP)
4	E, H (A, B)	{[5-(6-AMINO-PURIN-7-YL)-3,4-DIHYDROXY-TETRAHYDRO-FURAN-2-YLMETHOXY]-HYDROXY-PHOSPHORYLMETHYL}-PHOSPHONIC ACID MONO-[2-(4-HYDROXY-6-METHOXY-7-METHYL-3-OXO-1,3-DIHYDRO-ISOBENZOFURAN-5-YL)-ETHYL] ESTER	non-polymer		645.5	2	Chemie (MYD)
5	I, J, K, L, M... (B)	UNKNOWN LIGAND	non-polymer		103.1	11	Chemie (UNL)
6	T, U (A, B)	water	water		18.0	93	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	111749.7
Non-Polymers*	Number of molecules	17
	Total formula weight	3151.8
All*	Total formula weight	114901.5

*Water molecules are not included.