1NEZ
The Crystal Structure of a TL/CD8aa Complex at 2.1A resolution:Implications for Memory T cell Generation, Co-receptor Preference and Affinity
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | H-2 class I histocompatibility antigen, TLA(C) alpha chain | polymer | 274 | 31660.0 | 1 | UniProt (P14433) Pfam (PF00129) Pfam (PF07654) UniProt (by SIFTS) (P14432) | TL | |
| 2 | B (B) | Beta-2-microglobulin | polymer | 99 | 11704.4 | 1 | UniProt (P01887) Pfam (PF07654) | ||
| 3 | C, D (G, H) | T-cell surface glycoprotein CD8 alpha chain | polymer | 128 | 14397.5 | 2 | UniProt (P01731) Pfam (PF07686) | T-cell surface glycoprotein LYT-2, CD8AA | |
| 4 | E, F, G, H (G, H) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 4 | Chemie (NAG) | |||
| 5 | I, J, K, L (A, B, G, H) | water | water | 18.0 | 164 | Chemie (HOH) |
Sequence modifications
G, H: 1 - 122 (UniProt: P01731)
| PDB | External Database | Details |
|---|---|---|
| Ser 123 | - | cloning artifact |
| Ser 124 | - | cloning artifact |
| Ala 125 | - | cloning artifact |
| Leu 126 | - | cloning artifact |
| Val 127 | - | cloning artifact |
| Pro 128 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 72159.5 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 884.8 | |
| All* | Total formula weight | 73044.3 |
