1N8Z
Crystal structure of extracellular domain of human HER2 complexed with Herceptin Fab
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Herceptin Fab (antibody) - light chain | polymer | 214 | 23466.0 | 1 | Mus musculus Homo sapiens (mouse/human) | ||
| 2 | B (B) | Herceptin Fab (antibody) - heavy chain | polymer | 220 | 23425.2 | 1 | Mus musculus Homo sapiens (mouse/human) | ||
| 3 | C (C) | Receptor protein-tyrosine kinase erbB-2 | polymer | 607 | 66989.1 | 1 | UniProt (P04626) Pfam (PF01030) Pfam (PF00757) Pfam (PF14843) | Homo sapiens (human) | Tyrosine kinase-type cell surface receptor HER2 |
| 4 | D, E (C) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
| 5 | F (C) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 6 | G, H, I (A, B, C) | water | water | 18.0 | 79 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 113880.3 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 538.5 | |
| All* | Total formula weight | 114418.8 |
