1N3E

Crystal structure of I-CreI bound to a palindromic DNA sequence I (palindrome of left side of wildtype DNA target sequence)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C, E, G (C, E, I, K)	5'-D(*CP*GP*AP*AP*AP*AP*CP*GP*TP*CP*GP*TP*AP*C)-3'	polymer	14	4273.8	4
2	B, D, F, H (D, F, J, L)	5'-D(P*GP*AP*CP*GP*TP*TP*TP*TP*CP*G)-3'	polymer	10	3051.0	4
3	I, J, K, L (A, B, G, H)	DNA endonuclease I-CreI	polymer	163	18722.6	4	UniProt (P05725) Pfam (PF00961)	Chlamydomonas reinhardtii	23S rRNA intron protein
4	M, N, O, P, Q... (C, D, F, I, J...)	CALCIUM ION	non-polymer		40.1	6	Chemie (CA)
5	S, T, U, V (A, B, G, H)	SODIUM ION	non-polymer		23.0	4	Chemie (NA)
6	AA, BA, CA, DA, EA... (I, J, K, L, A...)	water	water		18.0	233	Chemie (HOH)

Sequence modifications

A, B, G, H: 1 - 163 (UniProt: P05725)

PDB	External Database	Details
Thr 42	Ala 42	SEE REMARK 999
Glu 110	Trp 110	SEE REMARK 999
Gln 111	Arg 111	SEE REMARK 999

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	104189.5
Non-Polymers*	Number of molecules	10
	Total formula weight	332.4
All*	Total formula weight	104521.9

*Water molecules are not included.