1N2J
Crystal Structure of a Pantothenate Synthetase from M. tuberculosis in complex with pantoate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | pantothenate synthetase | polymer | 300 | 31500.1 | 2 | UniProt (P0A5R0) Pfam (PF02569) UniProt (by SIFTS) (P9WIL5) In PDB | Mycobacterium tuberculosis | Pantoate--beta-alanine ligase, Pantoate activating enzyme |
| 2 | A, B | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 3 | A, B | PANTOATE | non-polymer | 147.1 | 2 | Chemie (PAF) | |||
| 4 | A, B | BETA-ALANINE | non-polymer | 89.1 | 2 | Chemie (BAL) | |||
| 5 | A, B | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
| 6 | B | ETHANOL | non-polymer | 46.1 | 5 | Chemie (EOH) | |||
| 7 | water | water | 18.0 | 305 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 300 (UniProt: P0A5R0)
| PDB | External Database | Details |
|---|---|---|
| Ala 2 | Thr 2 | engineered mutation |
| Gly 77 | Glu 77 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 63000.2 | |
| Non-Polymers* | Number of molecules | 15 |
| Total formula weight | 1267.3 | |
| All* | Total formula weight | 64267.5 |
