1N2E
Crystal Structure of a Pantothenate Synthetase from M. tuberculosis in complex with AMPCPP and pantoate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | pantothenate synthetase | polymer | 300 | 31500.1 | 2 | UniProt (P0A5R0) Pfam (PF02569) UniProt (by SIFTS) (P9WIL5) In PDB | Mycobacterium tuberculosis | Pantoate--beta-alanine ligase, Pantoate activating enzyme |
| 2 | A, B | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 3 | A, B | DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER | non-polymer | 505.2 | 2 | Chemie (APC) | |||
| 4 | A | PANTOATE | non-polymer | 147.1 | 1 | Chemie (PAF) | |||
| 5 | A, B | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 6 | A, B | ETHANOL | non-polymer | 46.1 | 4 | Chemie (EOH) | |||
| 7 | B | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 8 | water | water | 18.0 | 408 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 300 (UniProt: P0A5R0)
| PDB | External Database | Details |
|---|---|---|
| Ala 2 | Thr 2 | engineered mutation |
| Gly 77 | Glu 77 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 63000.2 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 1742.5 | |
| All* | Total formula weight | 64742.7 |
