1MX1
Crystal Structure of Human Liver Carboxylesterase in complex with tacrine
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B, C, D, E... | liver Carboxylesterase I | polymer | 548 | 60511.3 | 6 | UniProt (P23141) Pfam (PF00135) In PDB | Homo sapiens (human) | hCEv, Acyl coenzyme A:cholesterol acyltransferase, ACAT, Monocyte/macrophage serine esterase, HMSE, Serine esterase 1 |
2 | G | 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G07375KG) | |||
3 | A, B, D, E, F | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 6 | Chemie (NAG) | |||
4 | A, B, D, E | N-acetyl-alpha-neuraminic acid | non-polymer | 309.3 | 4 | Chemie (SIA) | |||
5 | A, B, C, D, E... | TACRINE | non-polymer | 198.3 | 6 | Chemie (THA) | |||
6 | water | water | 18.0 | 2117 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F: 1019 - 1567 (UniProt: P23141)
PDB | External Database | Details |
---|---|---|
- | Gln 362 | deletion |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 6 |
Total formula weight | 363068.0 | |
Branched | Number of molecules | 1 |
Total formula weight | 424.4 | |
Non-Polymers* | Number of molecules | 16 |
Total formula weight | 3753.9 | |
All* | Total formula weight | 367246.3 |