1MX1
Crystal Structure of Human Liver Carboxylesterase in complex with tacrine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | liver Carboxylesterase I | polymer | 548 | 60511.3 | 6 | UniProt (P23141) Pfam (PF00135) | Homo sapiens (human) | hCEv, Acyl coenzyme A:cholesterol acyltransferase, ACAT, Monocyte/macrophage serine esterase, HMSE, Serine esterase 1 |
| 2 | G (G) | 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G07375KG) | |||
| 3 | H, K, O, R, U... (A, B, D, E, F) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 6 | Chemie (NAG) | |||
| 4 | I, L, P, S (A, B, D, E) | N-acetyl-alpha-neuraminic acid | non-polymer | 309.3 | 4 | Chemie (SIA) | |||
| 5 | J, M, N, Q, T... (A, B, C, D, E...) | TACRINE | non-polymer | 198.3 | 6 | Chemie (THA) | |||
| 6 | AA, BA, CA, X, Y... (D, E, F, A, B...) | water | water | 18.0 | 2117 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F: 1019 - 1567 (UniProt: P23141)
| PDB | External Database | Details |
|---|---|---|
| - | Gln 362 | deletion |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 363068.0 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 424.4 | |
| Non-Polymers* | Number of molecules | 16 |
| Total formula weight | 3753.9 | |
| All* | Total formula weight | 367246.3 |
