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1MU6

Crystal Structure of Thrombin in Complex with L-378,622

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
THROMBINpolymer364096.51UniProt (P00734)
Pfam (PF09396)
Homo sapiens (human)Coagulation factor II
2B
(B)
THROMBINpolymer25929780.21UniProt (P00734)
Pfam (PF00089)
Homo sapiens (human)Coagulation factor II
3C
(C)
HIRUDIN IIBpolymer111491.51UniProt (P28506)
UniProt (by SIFTS) (P28504)
Hirudo medicinalis
4D
(B)
2-(6-CHLORO-3-{[2,2-DIFLUORO-2-(2-PYRIDINYL)ETHYL]AMINO}-2-OXO-1(2H)-PYRAZINYL)-N-[(2-FLUORO-6-PYRIDINYL)METHYL]ACETAMIDEnon-polymer432.41Chemie (CDA)
5E, F, G
(A, B, C)
waterwater18.0103Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight35368.3
Non-Polymers*Number of molecules1
Total formula weight432.4
All*Total formula weight35800.7
*Water molecules are not included.

246031

PDB entries from 2025-12-10

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