1MSM
The HIV protease (mutant Q7K L33I L63I) complexed with KNI-764 (an inhibitor)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | POL polyprotein | polymer | 99 | 10804.8 | 2 | UniProt (P03367) Pfam (PF00077) In PDB | Human immunodeficiency virus 1 | |
| 2 | B | (4R)-3-{(2S,3S)-2-hydroxy-3-[(3-hydroxy-2-methylbenzoyl)amino]-4-phenylbutanoyl}-5,5-dimethyl-N-(2-methylbenzyl)-1,3-thiazolidine-4-carboxamide | non-polymer | 575.7 | 1 | BIRD (PRD_000566) Chemie (JE2) | |||
| 3 | water | water | 18.0 | 145 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 99 (UniProt: P03367)
| PDB | External Database | Details |
|---|---|---|
| Lys 7 | Gln 75 | engineered mutation |
| Ile 33 | Leu 101 | engineered mutation |
| Ile 63 | Leu 131 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 21609.6 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 575.7 | |
| All* | Total formula weight | 22185.3 |
