1MRQ
Crystal structure of human 20alpha-HSD in ternary complex with NADP and 20alpha-hydroxy-progesterone
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Aldo-keto reductase family 1 member C1 | polymer | 323 | 36836.3 | 1 | UniProt (Q04828) Pfam (PF00248) | Homo sapiens (human) | 20alpha-hydroxysteroid dehydrogenase, Trans-1,2- dihydrobenzene-1,2-diol dehydrogenase, High-affinity hepatic bile acid-binding protein, HBAB, Chlordecone reductase homolog HAKRC, Dihydrodiol dehydrogenase 2, DD2 |
| 2 | B (A) | NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 743.4 | 1 | Chemie (NAP) | |||
| 3 | C (A) | PROGESTERONE | non-polymer | 314.5 | 1 | Chemie (STR) | |||
| 4 | D (A) | BETA-MERCAPTOETHANOL | non-polymer | 78.1 | 1 | Chemie (BME) | |||
| 5 | E (A) | water | water | 18.0 | 321 | Chemie (HOH) |
Sequence modifications
A: 2 - 323 (UniProt: Q04828)
| PDB | External Database | Details |
|---|---|---|
| Gln 1 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 36836.3 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 1136.0 | |
| All* | Total formula weight | 37972.3 |
