1MRC
PREPARATION, CHARACTERIZATION AND CRYSTALLIZATION OF AN ANTIBODY FAB FRAGMENT THAT RECOGNIZES RNA. CRYSTAL STRUCTURES OF NATIVE FAB AND THREE FAB-MONONUCLEOTIDE COMPLEXES
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | L | IGG2B-KAPPA JEL103 FAB (LIGHT CHAIN) | polymer | 219 | 24180.9 | 1 | PIR (PC4203) | Mus musculus (house mouse) | |
| 2 | H | IGG2B-KAPPA JEL103 FAB (HEAVY CHAIN) | polymer | 215 | 23020.6 | 1 | GenBank (387221) | Mus musculus (house mouse) | |
| 3 | L | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 4 | L | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 5 | L | IMIDAZOLE | non-polymer | 69.1 | 1 | Chemie (IMD) | |||
| 6 | water | water | 18.0 | 72 | Chemie (HOH) |
Sequence modifications
L: 1 - 214 (PIR: PC4203)
H: 2 - 227 (GenBank: 387221)
| PDB | External Database | Details |
|---|---|---|
| Val 3 | Leu 3 | CONFLICT |
| Leu 27 | Ile 29 | CONFLICT |
| Ser 27 | Thr 32 | CONFLICT |
| His 34 | Glu 39 | CONFLICT |
| Phe 87 | Tyr 92 | CONFLICT |
| Ser 89 | Phe 94 | CONFLICT |
| Ser 91 | Gly 96 | CONFLICT |
| Thr 92 | Ser 97 | CONFLICT |
| Lys 153 | Ser 158 | CONFLICT |
| Asn 167 | Asp 172 | CONFLICT |
| PDB | External Database | Details |
|---|---|---|
| Lys 13 | Arg 13 | CONFLICT |
| Ala 16 | Thr 16 | CONFLICT |
| Leu 20 | Met 20 | CONFLICT |
| Ser 25 | Ala 25 | CONFLICT |
| Ser 31 | Asn 31 | CONFLICT |
| Met 34 | Ile 34 | CONFLICT |
| Gln 35 | Gly 35 | CONFLICT |
| Gln 39 | Glu 39 | CONFLICT |
| Gln 43 | His 43 | CONFLICT |
| Glu 50 | Asp 50 | CONFLICT |
| Asp 51 | Tyr 52 | CONFLICT |
| Ser 53 | Gly 54 | CONFLICT |
| Asp 54 | Gly 55 | CONFLICT |
| Ser 55 | Gly 56 | CONFLICT |
| Tyr 56 | Phe 57 | CONFLICT |
| Gln 61 | Glu 62 | CONFLICT |
| Lys 62 | Asn 63 | CONFLICT |
| Val 71 | Ala 72 | CONFLICT |
| Val 89 | Ile 93 | CONFLICT |
| Tyr 91 | His 95 | CONFLICT |
| - | Arg 98 | DELETION |
| - | Gly 99 | DELETION |
| - | Ile 100 | DELETION |
| - | Tyr 101 | DELETION |
| - | Tyr 102 | DELETION |
| Leu 95 | Ser 104 | CONFLICT |
| Arg 96 | Ser 105 | CONFLICT |
| Gly 97 | Pro 106 | CONFLICT |
| Tyr 102 | Ser 110 | CONFLICT |
| Leu 140 | Ser 146 | CONFLICT |
| Ser 151 | Pro 157 | CONFLICT |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 47201.5 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 230.6 | |
| All* | Total formula weight | 47432.0 |
