1MQB
Crystal Structure of Ephrin A2 (ephA2) Receptor Protein Kinase
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Ephrin type-A receptor 2 | polymer | 333 | 37783.4 | 2 | UniProt (P29317) Pfam (PF07714) | Homo sapiens (human) | EphA2 receptor tyrosine kinase, Tyrosine-protein kinase receptor ECK, Epithelial cell kinase |
| 2 | C, D (A, B) | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | non-polymer | 506.2 | 2 | Chemie (ANP) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 66 | Chemie (HOH) |
Sequence modifications
A, B: 596 - 900 (UniProt: P29317)
| PDB | External Database | Details |
|---|---|---|
| Met 568 | - | cloning artifact |
| Ser 569 | - | cloning artifact |
| Tyr 570 | - | cloning artifact |
| Tyr 571 | - | cloning artifact |
| His 572 | - | cloning artifact |
| His 573 | - | cloning artifact |
| His 574 | - | cloning artifact |
| His 575 | - | cloning artifact |
| His 576 | - | cloning artifact |
| His 577 | - | cloning artifact |
| Asp 578 | - | cloning artifact |
| Tyr 579 | - | cloning artifact |
| Asp 580 | - | cloning artifact |
| Ile 581 | - | cloning artifact |
| Pro 582 | - | cloning artifact |
| Thr 583 | - | cloning artifact |
| Thr 584 | - | cloning artifact |
| Glu 585 | - | cloning artifact |
| Asn 586 | - | cloning artifact |
| Leu 587 | - | cloning artifact |
| Tyr 588 | - | cloning artifact |
| Phe 589 | - | cloning artifact |
| Gln 590 | - | cloning artifact |
| Gly 591 | - | cloning artifact |
| Ala 592 | - | cloning artifact |
| Met 593 | - | cloning artifact |
| Gly 594 | - | cloning artifact |
| Ser 595 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 75566.8 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 1012.4 | |
| All* | Total formula weight | 76579.2 |
