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1MP8

Crystal structure of Focal Adhesion Kinase (FAK)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
focal adhesion kinase 1polymer28132120.11UniProt (Q05397)
Pfam (PF07714)
Homo sapiens (human)fak, fadk 1, pp125fak, protein-tyrosine kinase 2
2B
(A)
ADENOSINE-5'-DIPHOSPHATEnon-polymer427.21Chemie (ADP)
3C
(A)
waterwater18.0233Chemie (HOH)
Sequence modifications
A: 411 - 686 (UniProt: Q05397)
PDBExternal DatabaseDetails
Gly 406-cloning artifact
Ala 407-cloning artifact
Met 408-cloning artifact
Gly 409-cloning artifact
Ser 410-cloning artifact
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight32120.1
Non-Polymers*Number of molecules1
Total formula weight427.2
All*Total formula weight32547.3
*Water molecules are not included.

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PDB entries from 2025-07-23

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