1MJN
Crystal Structure of the intermediate affinity aL I domain mutant
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Integrin alpha-L | polymer | 179 | 20362.3 | 1 | UniProt (P20701) Pfam (PF00092) | Homo sapiens | Leukocyte adhesion glycoprotein LFA-1 alpha chain, Leukocyte function associated molecule 1, alpha chain, CD11a |
| 2 | B (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 3 | C (A) | water | water | 18.0 | 322 | Chemie (HOH) |
Sequence modifications
A: 128 - 306 (UniProt: P20701)
| PDB | External Database | Details |
|---|---|---|
| Cys 161 | Leu 186 | engineered mutation |
| Cys 299 | Phe 324 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 20362.3 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 24.3 | |
| All* | Total formula weight | 20386.6 |
