1MFQ

Crystal Structure Analysis of a Ternary S-Domain Complex of Human Signal Recognition Particle

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	7S RNA of human SRP	polymer	128	41566.7	1		Homo sapiens (human)
2	B (B)	signal recognition particle 19kDa protein	polymer	108	12561.7	1	UniProt (P09132) Pfam (PF01922)	Homo sapiens (human)	SRP19
3	C (C)	signal recognition particle 54kDa protein	polymer	129	14733.0	1	UniProt (P61011) Pfam (PF02978)	Homo sapiens (human)	SRP54
4	D, E, F, G, H (A)	MAGNESIUM ION	non-polymer		24.3	5	Chemie (MG)
5	I, J (B, C)	CHLORIDE ION	non-polymer		35.5	2	Chemie (CL)
6	K, L, M (A, B, C)	water	water		18.0	19	Chemie (HOH)

Sequence modifications

B: 14 - 120 (UniProt: P09132)

PDB	External Database	Details
Met 13	-	initiating methionine

C: 323 - 441 (UniProt: P61011)

PDB	External Database	Details
Met 313	-	expression tag
Arg 314	-	expression tag
Gly 315	-	expression tag
Ser 316	-	expression tag
His 317	-	expression tag
His 318	-	expression tag
His 319	-	expression tag
His 320	-	expression tag
His 321	-	expression tag
His 322	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	68861.4
Non-Polymers*	Number of molecules	7
	Total formula weight	192.4
All*	Total formula weight	69053.9

*Water molecules are not included.