1MEN

complex structure of human GAR Tfase and substrate beta-GAR

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C (A, B, C)	Phosphoribosylglycinamide formyltransferase	polymer	223	24122.6	3	UniProt (P22102) Pfam (PF00551)	Homo sapiens (human)	GART, GAR transformylase, 5'-phosphoribosylglycinamide transformylase
2	D, E, F (A, B, C)	GLYCINAMIDE RIBONUCLEOTIDE	non-polymer		284.2	3	Chemie (GAR)
3	G, H, I (A, B, C)	water	water		18.0	128	Chemie (HOH)

Sequence modifications

A, B, C: 3 - 203 (UniProt: P22102)

PDB	External Database	Details
Ala -10	-	expression tag
Ser -9	-	expression tag
Met -8	-	expression tag
Thr -7	-	expression tag
Gly -6	-	expression tag
Gly -5	-	expression tag
Gln -4	-	expression tag
Gln -3	-	expression tag
Met -2	-	expression tag
Gly -1	-	expression tag
Arg 0	-	expression tag
Ile 1	-	expression tag
Leu 2	-	expression tag
Pro 204	-	expression tag
Leu 205	-	expression tag
Glu 206	-	expression tag
His 207	-	expression tag
His 208	-	expression tag
His 209	-	expression tag
His 210	-	expression tag
His 211	-	expression tag
His 212	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	72367.9
Non-Polymers*	Number of molecules	3
	Total formula weight	852.5
All*	Total formula weight	73220.4

*Water molecules are not included.