1MDI
HIGH RESOLUTION SOLUTION NMR STRUCTURE OF MIXED DISULFIDE INTERMEDIATE BETWEEN MUTANT HUMAN THIOREDOXIN AND A 13 RESIDUE PEPTIDE COMPRISING ITS TARGET SITE IN HUMAN NFKB
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | THIOREDOXIN | polymer | 105 | 11592.1 | 1 | UniProt (P10599) Pfam (PF00085) In PDB | Homo sapiens (human) | |
| 2 | B | TARGET SITE IN HUMAN NFKB | polymer | 13 | 1557.8 | 1 | UniProt (P19838) In PDB | ||
| 3 | water | water | 18.0 | 6 | Chemie (HOH) |
Sequence modifications
A: 2 - 105 (UniProt: P10599)
| PDB | External Database | Details |
|---|---|---|
| Ala 35 | Cys 34 | conflict |
| Ala 62 | Cys 61 | conflict |
| Ala 69 | Cys 68 | conflict |
| Ala 73 | Cys 72 | conflict |
| Thr 74 | Met 73 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 13149.9 | |
| All* | Total formula weight | 13149.9 |
