1MCO
THREE-DIMENSIONAL STRUCTURE OF A HUMAN IMMUNOGLOBULIN WITH A HINGE DELETION
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | L | IGG1 MCG INTACT ANTIBODY (LIGHT CHAIN) | polymer | 216 | 22835.0 | 1 | PIR (S14675) | Homo sapiens (human) | |
| 2 | H | IGG1 MCG INTACT ANTIBODY (HEAVY CHAIN) | polymer | 428 | 46898.9 | 1 | GenBank (243866) | Homo sapiens (human) | |
| 3 | A | N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-L-gulopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1916.7 | 1 | In PDB GlyTouCan (G18746ZC) |
Sequence modifications
L: 2 - 216 (PIR: S14675)
H: 3 - 428 (GenBank: 243866)
| PDB | External Database | Details |
|---|---|---|
| Ile 20 | Phe 39 | conflict |
| Thr 23 | Ser 42 | conflict |
| Val 29 | Ile 48 | conflict |
| Gly 31 | Asn 50 | conflict |
| Gln 39 | Arg 58 | conflict |
| Ala 42 | Pro 61 | conflict |
| Val 48 | Leu 67 | conflict |
| Ile 49 | Met 68 | conflict |
| Asn 54 | Thr 73 | conflict |
| Asp 62 | Asn 81 | conflict |
| Glu 94 | Ala 113 | conflict |
| Asp 97 | Asn 116 | conflict |
| Asn 98 | Ser 117 | conflict |
| Phe 99 | Leu 118 | conflict |
| Val 100 | Ile 119 | conflict |
| Thr 103 | Gly 122 | conflict |
| Lys 106 | Arg 125 | conflict |
| Val 107 | Leu 126 | conflict |
| Asn 116 | Ala 135 | conflict |
| Thr 118 | Ser 137 | conflict |
| Glu 136 | Leu 155 | conflict |
| Gly 156 | Ser 175 | conflict |
| Lys 167 | Thr 186 | conflict |
| PDB | External Database | Details |
|---|---|---|
| - | Gln 22 | deletion |
| Lys 13 | Arg 32 | conflict |
| Glu 16 | Gln 35 | conflict |
| Ala 17 | Thr 36 | conflict |
| Asp 27 | - | insertion |
| Ser 28 | Phe 46 | conflict |
| Ile 29 | Thr 47 | conflict |
| Asn 30 | Phe 48 | conflict |
| Ile 32 | - | insertion |
| Leu 33 | Asp 50 | conflict |
| Tyr 34 | Phe 51 | conflict |
| Trp 36 | Met 53 | conflict |
| Ser 37 | Asn 54 | conflict |
| Ile 39 | Val 56 | conflict |
| Lys 45 | Arg 62 | conflict |
| Tyr 52 | Phe 69 | conflict |
| - | Arg 71 | deletion |
| - | Asp 72 | deletion |
| Tyr 54 | Lys 73 | conflict |
| Tyr 55 | Ala 74 | conflict |
| Ser 56 | Lys 75 | conflict |
| Ser 58 | Tyr 77 | conflict |
| - | Thr 79 | deletion |
| - | Glu 80 | deletion |
| Gly 61 | - | insertion |
| Leu 65 | Val 85 | conflict |
| Ser 67 | Gly 87 | conflict |
| Ile 71 | Met 91 | conflict |
| Ser 72 | Leu 92 | conflict |
| Asn 74 | Asp 94 | conflict |
| Tyr 81 | Ser 101 | conflict |
| Ser 82 | Leu 102 | conflict |
| Lys 83 | Arg 103 | conflict |
| Val 100 | Glu 120 | conflict |
| Pro 101 | Gly 121 | conflict |
| Leu 102 | His 122 | conflict |
| Val 103 | Thr 123 | conflict |
| Val 104 | Ala 124 | conflict |
| Asn 105 | Ala 125 | conflict |
| - | Phe 127 | deletion |
| - | Asp 128 | deletion |
| - | Tyr 129 | deletion |
| Thr 111 | Ser 134 | conflict |
| Gln 152 | Glu 175 | conflict |
| Arg 214 | Lys 237 | conflict |
| - | Glu 239 | deletion |
| - | Pro 240 | deletion |
| - | Lys 241 | deletion |
| - | Ser 242 | deletion |
| - | Cys 243 | deletion |
| - | Asp 244 | deletion |
| - | Lys 245 | deletion |
| - | Thr 246 | deletion |
| - | His 247 | deletion |
| - | Thr 248 | deletion |
| - | Cys 249 | deletion |
| - | Pro 250 | deletion |
| - | Pro 251 | deletion |
| - | Cys 252 | deletion |
| - | Pro 253 | deletion |
| Gln 257 | Glu 295 | conflict |
| Gln 268 | Glu 306 | conflict |
| Gln 279 | Glu 317 | conflict |
| Asn 297 | Asp 335 | conflict |
| Asp 300 | Asn 338 | conflict |
| Glu 341 | Asp 379 | conflict |
| Met 343 | Leu 381 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 69734.0 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 1916.7 | |
| All* | Total formula weight | 71650.7 |
