1MCJ
PRINCIPLES AND PITFALLS IN DESIGNING SITE DIRECTED PEPTIDE LIGANDS
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | IMMUNOGLOBULIN LAMBDA DIMER MCG (LIGHT CHAIN) | polymer | 216 | 22819.1 | 2 | PIR (S14675) | Homo sapiens (human) | |
2 | P | PEPTIDE N-ACETYL-D-PHE-L-HIS-D-PRO-NH2 | polymer | 5 | 424.5 | 1 | |||
3 | A | ACETYL GROUP | non-polymer | 44.1 | 1 | Chemie (ACE) | |||
4 | P | D-PHENYLALANINE | non-polymer | 165.2 | 1 | Chemie (DPN) | |||
5 | P | D-PROLINE | non-polymer | 115.1 | 1 | Chemie (DPR) | |||
6 | P | AMINO GROUP | non-polymer | 16.0 | 1 | Chemie (NH2) |
Sequence modifications
A, B: 2 - 216 (PIR: S14675)
PDB | External Database | Details |
---|---|---|
Ile 20 | Phe 39 | CONFLICT |
Thr 23 | Ser 42 | CONFLICT |
Val 29 | Ile 48 | CONFLICT |
Gly 31 | Asn 50 | CONFLICT |
Gln 39 | Arg 58 | CONFLICT |
Ala 42 | Pro 61 | CONFLICT |
Val 48 | Leu 67 | CONFLICT |
Ile 49 | Met 68 | CONFLICT |
Asn 54 | Thr 73 | CONFLICT |
Asp 62 | Asn 81 | CONFLICT |
Glu 94 | Ala 113 | CONFLICT |
Asp 97 | Asn 116 | CONFLICT |
Asn 98 | Ser 117 | CONFLICT |
Phe 99 | Leu 118 | CONFLICT |
Val 100 | Ile 119 | CONFLICT |
Thr 103 | Gly 122 | CONFLICT |
Lys 106 | Arg 125 | CONFLICT |
Val 107 | Leu 126 | CONFLICT |
Asn 116 | Ala 135 | CONFLICT |
Thr 118 | Ser 137 | CONFLICT |
Gly 156 | Ser 175 | CONFLICT |
Lys 167 | Thr 186 | CONFLICT |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 46062.7 | |
Non-Polymers* | Number of molecules | 4 |
Total formula weight | 340.4 | |
All* | Total formula weight | 46403.1 |