1MCI
PRINCIPLES AND PITFALLS IN DESIGNING SITE DIRECTED PEPTIDE LIGANDS
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | IMMUNOGLOBULIN LAMBDA DIMER MCG (LIGHT CHAIN) | polymer | 216 | 22819.1 | 2 | PIR (S14675) | Homo sapiens (human) | |
| 2 | C (P) | PEPTIDE N-ACETYL-D-PHE-L-HIS-D-PRO-OH | polymer | 4 | 426.5 | 1 |
Sequence modifications
A, B: 2 - 216 (PIR: S14675)
| PDB | External Database | Details |
|---|---|---|
| Ile 20 | Phe 39 | conflict |
| Thr 23 | Ser 42 | conflict |
| Val 29 | Ile 48 | conflict |
| Gly 31 | Asn 50 | conflict |
| Gln 39 | Arg 58 | conflict |
| Ala 42 | Pro 61 | conflict |
| Val 48 | Leu 67 | conflict |
| Ile 49 | Met 68 | conflict |
| Asn 54 | Thr 73 | conflict |
| Asp 62 | Asn 81 | conflict |
| Glu 94 | Ala 113 | conflict |
| Asp 97 | Asn 116 | conflict |
| Asn 98 | Ser 117 | conflict |
| Phe 99 | Leu 118 | conflict |
| Val 100 | Ile 119 | conflict |
| Thr 103 | Gly 122 | conflict |
| Lys 106 | Arg 125 | conflict |
| Val 107 | Leu 126 | conflict |
| Asn 116 | Ala 135 | conflict |
| Thr 118 | Ser 137 | conflict |
| Gly 156 | Ser 175 | conflict |
| Lys 167 | Thr 186 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 46064.6 | |
| All* | Total formula weight | 46064.6 |
