1MA3
Structure of a Sir2 enzyme bound to an acetylated p53 peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Transcriptional regulatory protein, Sir2 family | polymer | 253 | 28537.0 | 1 | UniProt (O30124) Pfam (PF02146) | Archaeoglobus fulgidus | Sir2-Af2 |
| 2 | B (B) | Cellular tumor antigen p53 | polymer | 18 | 2139.5 | 1 | UniProt (P04637) | Tumor suppressor p53, Phosphoprotein, p53, Antigen NY-CO-13 | |
| 3 | C (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 4 | D (B) | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID | non-polymer | 195.2 | 1 | Chemie (MES) | |||
| 5 | E, F (A, B) | water | water | 18.0 | 129 | Chemie (HOH) |
Sequence modifications
B: 1 - 18 (UniProt: P04637)
| PDB | External Database | Details |
|---|---|---|
| Aly 11 | Lys 382 | MODIFIED RESIDUE |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 30676.5 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 260.6 | |
| All* | Total formula weight | 30937.2 |
