1M9D
X-ray crystal structure of Cyclophilin A/HIV-1 CA N-terminal domain (1-146) O-type chimera Complex.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Cyclophilin A | polymer | 165 | 18036.5 | 2 | UniProt (P62937) Pfam (PF00160) | Homo sapiens (human) | Peptidyl-prolyl cis-trans isomerase A, PPIase, Rotamase, Cyclosporin A-binding protein |
| 2 | C, D (C, D) | HIV-1 Capsid | polymer | 146 | 16191.6 | 2 | UniProt (Q72497) UniProt (by SIFTS) (P12497) | Human immunodeficiency virus 1 | |
| 3 | E, F, G, H (A, B, C, D) | water | water | 18.0 | 584 | Chemie (HOH) |
Sequence modifications
C, D: 1 - 146 (UniProt: Q72497)
| PDB | External Database | Details |
|---|---|---|
| Thr 83 | Leu 215 | engineered mutation |
| Pro 86 | Val 218 | engineered mutation |
| Ala 87 | His 219 | engineered mutation |
| Met 88 | Ala 220 | engineered mutation |
| Leu 91 | Ile 223 | engineered mutation |
| Pro 92 | Ala 224 | engineered mutation |
| Ile 96 | Met 228 | engineered mutation |
| His 120 | Asn 252 | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 68456.1 | |
| All* | Total formula weight | 68456.1 |
