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1M7A

CANDIDA ALBICANS DIHYDROFOLATE REDUCTASE COMPLEXED WITH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE (NADPH) AND 7-[2-methoxy-1-(methoxymethyl)ethyl]-7H-pyrrolo[3,2-f] quinazoline-1,3-diamine (GW557)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, BDIHYDROFOLATE REDUCTASEpolymer19222194.52UniProt (P22906)
Pfam (PF00186)
In PDB
Candida albicansDHFR
2A, BNADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATEnon-polymer745.42Chemie (NDP)
3A, B7-[2-METHOXY-1-(METHOXYMETHYL)ETHYL]-7H-PYRROLO[3,2-F] QUINAZOLINE-1,3-DIAMINEnon-polymer301.32Chemie (MQU)
4waterwater18.0342Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight44389.1
Non-Polymers*Number of molecules4
Total formula weight2093.5
All*Total formula weight46482.6
*Water molecules are not included.

222415

PDB entries from 2024-07-10

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