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1M4H

Crystal Structure of Beta-secretase complexed with Inhibitor OM00-3

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
beta-Secretasepolymer39143627.22UniProt (P56817)
Pfam (PF00026)
Homo sapiens (human)Memapsin-2
2C, D
(C, D)
Inhibitor OM00-3polymer7936.12BIRD (PRD_000289)synthetic construct
3E, F, G, H
(A, B, C, D)
waterwater18.0450Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight89126.5
All*Total formula weight89126.5
*Water molecules are not included.

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PDB entries from 2025-06-18

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