1M2K
Sir2 homologue F159A mutant-ADP ribose complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Silent Information Regulator 2 | polymer | 249 | 27574.9 | 1 | UniProt (O28597) Pfam (PF02146) | Archaeoglobus fulgidus | transcriptional regulatory protein, Sir2 family |
| 2 | B (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 3 | C (A) | ADENOSINE-5-DIPHOSPHORIBOSE | non-polymer | 559.3 | 1 | Chemie (APR) | |||
| 4 | D (A) | water | water | 18.0 | 347 | Chemie (HOH) |
Sequence modifications
A: 1 - 245 (UniProt: O28597)
| PDB | External Database | Details |
|---|---|---|
| Ala 159 | Phe 159 | engineered mutation |
| Leu 246 | - | cloning artifact |
| Lys 247 | - | cloning artifact |
| Leu 248 | - | cloning artifact |
| Asn 249 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 27574.9 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 624.7 | |
| All* | Total formula weight | 28199.6 |
