1M1U
AN ISOLEUCINE-BASED ALLOSTERIC SWITCH CONTROLS AFFINITY AND SHAPE SHIFTING IN INTEGRIN CD11B A-DOMAIN
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Integrin alpha-M | polymer | 195 | 22261.3 | 1 | UniProt (P11215) Pfam (PF00092) | Homo sapiens (human) | CD11b |
| 2 | B (A) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 3 | C (A) | water | water | 18.0 | 39 | Chemie (HOH) |
Sequence modifications
A: 123 - 315 (UniProt: P11215)
| PDB | External Database | Details |
|---|---|---|
| Gly 121 | - | cloning artifact |
| Ser 122 | - | cloning artifact |
| Ser 128 | Cys 144 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 22261.3 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 40.1 | |
| All* | Total formula weight | 22301.4 |
