1M16

Human Acidic Fibroblast Growth Factor. 141 Amino Acid Form with Amino Terminal His Tag and Leu 44 Replaced with Phe (L44F), Leu 73 Replaced with Val (L73V), Val 109 Replaced with Leu (V109L) and Cys 117 Replaced with Val (C117V).

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	acidic fibroblast growth factor	polymer	146	16716.8	2	UniProt (P05230) Pfam (PF00167) In PDB	Homo sapiens (human)	Heparin-binding growth factor 1, HBGF-1, AFGF, Beta-endothelial cell growth factor, ECGF-beta
2	A, B	SULFATE ION	non-polymer		96.1	2	Chemie (SO4)
3	A, B	FORMIC ACID	non-polymer		46.0	2	Chemie (FMT)
4		water	water		18.0	211	Chemie (HOH)

Sequence modifications

A, B: 1 - 140 (UniProt: P05230)

PDB	External Database	Details
His 1	-	expression tag
His 1	-	expression tag
His 1	-	expression tag
His 1	-	expression tag
His 1	-	expression tag
His 1	-	expression tag
Phe 44	Leu 59	engineered mutation
Val 73	Leu 88	engineered mutation
Leu 109	Val 124	engineered mutation
Val 117	Cys 132	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	33433.5
Non-Polymers*	Number of molecules	4
	Total formula weight	284.2
All*	Total formula weight	33717.7

*Water molecules are not included.