1LVB

CATALYTICALLY INACTIVE TOBACCO ETCH VIRUS PROTEASE COMPLEXED WITH SUBSTRATE

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C (A, B)	CATALYTIC DOMAIN OF THE NUCLEAR INCLUSION PROTEIN A (NIA)	polymer	243	28004.7	2	UniProt (P04517) Pfam (PF00863)	Tobacco etch virus
2	B, D (C, D)	OLIGOPEPTIDE SUBSTRATE FOR THE PROTEASE	polymer	10	1159.2	2	UniProt (P04517)
3	E, F (A, B)	GLYCEROL	non-polymer		92.1	2	Chemie (GOL)
4	G, H, I, J (A, C, B, D)	water	water		18.0	181	Chemie (HOH)

Sequence modifications

A, B: 1 - 236 (UniProt: P04517)

PDB	External Database	Details
Ser -7	-	expression tag
His -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
Mse 82	Met 2119	modified residue
Mse 87	Met 2124	modified residue
Mse 121	Met 2158	modified residue
Mse 124	Met 2161	modified residue
Ala 151	Cys 2188	engineered mutation
Mse 187	Met 2224	modified residue
Mse 218	Met 2255	modified residue

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	58327.8
Non-Polymers*	Number of molecules	2
	Total formula weight	184.2
All*	Total formula weight	58512.0

*Water molecules are not included.