1LO5
Crystal structure of the D227A variant of Staphylococcal enterotoxin A in complex with human MHC class II
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | HLA class II histocompatibility antigen, DR alpha chain | polymer | 182 | 21155.9 | 1 | UniProt (P01903) Pfam (PF00993) Pfam (PF07654) | Homo sapiens (human) | MHC class II (HLA-DR1, Dra 0101)-chain A |
| 2 | B (B) | HLA class II histocompatibility antigen, DR-1 beta chain | polymer | 190 | 22080.7 | 1 | UniProt (P04229) Pfam (PF00969) Pfam (PF07654) UniProt (by SIFTS) (P01911) | Homo sapiens (human) | MHC class II (HLA-DR1, Drb1 0101)-chain B |
| 3 | C (C) | Hemagglutinin peptide | polymer | 13 | 1506.8 | 1 | |||
| 4 | D (D) | enterotoxin A | polymer | 233 | 27086.3 | 1 | UniProt (P0A0L2) Pfam (PF01123) Pfam (PF02876) | Staphylococcus aureus | |
| 5 | E, F, G (A, B, D) | water | water | 18.0 | 23 | Chemie (HOH) |
Sequence modifications
D: 1 - 233 (UniProt: P0A0L2)
| PDB | External Database | Details |
|---|---|---|
| Ala 227 | Asp 251 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 71829.7 | |
| All* | Total formula weight | 71829.7 |
