1LK3
ENGINEERED HUMAN INTERLEUKIN-10 MONOMER COMPLEXED TO 9D7 FAB FRAGMENT
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D (A, B) | Interleukin-10 | polymer | 160 | 18520.3 | 2 | UniProt (P22301) Pfam (PF00726) | Homo sapiens (human) | IL-10M1 (Engineered monomer of human Interleukin-10), IL-10, Cytokine synthesis inhibitory factor, CSIF |
| 2 | B, E (L, M) | 9D7 Light Chain | polymer | 210 | 22794.4 | 2 | Pfam (PF07654) UniProt (by SIFTS) (P01835) | Rattus norvegicus (Norway rat) | |
| 3 | C, F (H, I) | 9D7 Heavy Chain | polymer | 219 | 23529.4 | 2 | Pfam (PF07654) UniProt (by SIFTS) (P20759) | Rattus norvegicus (Norway rat) | |
| 4 | G, H, I, J, K... (A, L, H, B, M...) | water | water | 18.0 | 1203 | Chemie (HOH) |
Sequence modifications
A, B: 8 - 160 (UniProt: P22301)
| PDB | External Database | Details |
|---|---|---|
| Met 7 | - | initiating methionine |
| Gly 116 | - | insertion |
| Gly 116 | - | insertion |
| Gly 116 | - | insertion |
| Ser 116 | - | insertion |
| Gly 116 | - | insertion |
| Gly 116 | - | insertion |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 129688.4 | |
| All* | Total formula weight | 129688.4 |
