1LGC
INTERACTION OF A LEGUME LECTIN WITH THE N2 FRAGMENT OF HUMAN LACTOTRANSFERRIN OR WITH THE ISOLATED BIANTENNARY GLYCOPEPTIDE: ROLE OF THE FUCOSE MOIETY
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D, G (A, C, E) | Lectin beta-1 and beta-2 chains | polymer | 181 | 19860.9 | 3 | UniProt (P04122) Pfam (PF00139) | Lathyrus ochrus (yellow-flowered pea) | |
| 2 | B, E, H (H, I, J) | DIPEPTIDE | polymer | 2 | 260.2 | 3 | |||
| 3 | C, F, I (B, D, F) | Mannose/glucose-specific lectin alpha 2 chain | polymer | 53 | 5931.5 | 3 | UniProt (P12307) Pfam (PF00139) | Lol II | |
| 4 | J (G) | alpha-L-fucopyranose-(1-3)-[beta-D-galactopyranose-(1-4)]2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1771.6 | 1 | In PDB GlyTouCan (G90017UO) | |||
| 5 | K, L (K, L) | N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1713.6 | 2 | In PDB GlyTouCan (G84852GW) | |||
| 6 | M, O, Q (A, C, E) | CALCIUM ION | non-polymer | 40.1 | 3 | Chemie (CA) | |||
| 7 | N, P, R (A, C, E) | MANGANESE (II) ION | non-polymer | 54.9 | 3 | Chemie (MN) | |||
| 8 | S (E) | (4S)-2-METHYL-2,4-PENTANEDIOL | non-polymer | 118.2 | 1 | Chemie (MPD) | |||
| 9 | AA, BA, T, U, V... (J, F, A, H, B...) | water | water | 18.0 | 279 | Chemie (HOH) |
Sequence modifications
A, C, E: 1 - 181 (UniProt: P04122)
| PDB | External Database | Details |
|---|---|---|
| Pro 16 | Gln 16 | variant |
| Gly 168 | Ala 168 | variant |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 9 |
| Total formula weight | 78157.9 | |
| Branched | Number of molecules | 3 |
| Total formula weight | 5198.7 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 403.2 | |
| All* | Total formula weight | 83759.8 |
