1LGB

INTERACTION OF A LEGUME LECTIN WITH THE N2 FRAGMENT OF HUMAN LACTOTRANSFERRIN OR WITH THE ISOLATED BIANTENNARY GLYCOPEPTIDE: ROLE OF THE FUCOSE MOIETY

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	LEGUME ISOLECTIN II (ALPHA CHAIN)	polymer	181	19802.8	1	UniProt (P04122)	Lathyrus ochruss (Yellow-flowered pea)
2	B (B)	LEGUME ISOLECTIN II (BETA CHAIN)	polymer	53	5915.5	1	UniProt (P12307)	Lathyrus ochruss (Yellow-flowered pea)
3	C (C)	LACTOTRANSFERRIN (N2 FRAGMENT)	polymer	159	17541.8	1	UniProt (P02788) Pfam (PF00405)	Homo sapiens (Human)
4	D (D)	beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose	branched		1625.5	1	In PDB GlyTouCan (G58667NI)
5	E (A)	MANGANESE (II) ION	non-polymer		54.9	1	Chemie (MN) PubChem (27854)
6	F (A)	CALCIUM ION	non-polymer		40.1	1	Chemie (CA) PubChem (271)

Sequence modifications

A: 1 - 181 (UniProt: P04122)

PDB	External Database	Details
Pro 16	Gln 16	conflict
Ala 153	Lys 153	conflict
Gly 168	Ala 168	conflict

B: 1 - 53 (UniProt: P12307)

PDB	External Database	Details
Ala 47	Ser 47	conflict

C: 91 - 249 (UniProt: P02788)

PDB	External Database	Details
Lys 200	Arg 220	conflict

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	43260.0
Branched	Number of molecules	1
	Total formula weight	1625.5
Non-Polymers*	Number of molecules	2
	Total formula weight	95.0
All*	Total formula weight	44980.6

*Water molecules are not included.