1LE9

Crystal structure of a NF-kB heterodimer bound to the Ig/HIV-kB siti

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C (C, G)	5'-D(*TP*GP*GP*GP*AP*CP*TP*TP*TP*CP*CP*T)-3'	polymer	12	3644.4	2
2	B, D (D, H)	5'-D(*AP*AP*GP*GP*AP*AP*AP*GP*TP*CP*CP*C)-3'	polymer	12	3680.4	2
3	E, G (A, E)	NUCLEAR FACTOR NF-KAPPA-B P65 SUBUNIT	polymer	274	31115.2	2	UniProt (Q04207) Pfam (PF00554) Pfam (PF16179)	Mus musculus (house mouse)	NF-KB P65
4	F, H (B, F)	NUCLEAR FACTOR NF-KAPPA-B P50 SUBUNIT	polymer	313	35056.1	2	UniProt (P25799) Pfam (PF00554) Pfam (PF16179)	Mus musculus (house mouse)	NF-KB P50

Sequence modifications

A, E: 20 - 291 (UniProt: Q04207)

PDB	External Database	Details
Met 18	-	cloning artifact
Ala 19	-	cloning artifact

B, F: 39 - 350 (UniProt: P25799)

PDB	External Database	Details
Met 38	-	initiating methionine

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	146992.2
All*	Total formula weight	146992.2

*Water molecules are not included.