1LBB
Crystal structure of the GluR2 ligand binding domain mutant (S1S2J-N754D) in complex with kainate at 2.1 A resolution
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Glutamine receptor 2 | polymer | 263 | 29222.7 | 1 | UniProt (P19491) Pfam (PF10613) Pfam (PF00060) | Rattus norvegicus (Norway rat) | GLUR-2, GLUR-B, GLUR-K2, GLUTAMATE RECEPTOR IONOTROPIC AMPA 2 |
| 2 | B (A) | 3-(CARBOXYMETHYL)-4-ISOPROPENYLPROLINE | non-polymer | 213.2 | 1 | Chemie (KAI) PubChem (3816) PubChem (23616889) PubChem (10255) PubChem (73345) PubChem (45039619) PubChem (3083828) PubChem (5317452) PubChem (5318769) PubChem (6603893) PubChem (6453379) PubChem (6604705) PubChem (101994997) PubChem (10036135) PubChem (11095940) PubChem (135037246) | |||
| 3 | C (A) | water | water | 18.0 | 140 | Chemie (HOH) |
Sequence modifications
A: 3 - 117 (UniProt: P19491)
A: 120 - 263 (UniProt: P19491)
| PDB | External Database | Details |
|---|---|---|
| Gly 1 | - | cloning artifact |
| Ala 2 | - | cloning artifact |
| PDB | External Database | Details |
|---|---|---|
| Gly 118 | - | linker |
| Thr 119 | - | linker |
| Asp 242 | Asn 775 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 29222.7 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 213.2 | |
| All* | Total formula weight | 29435.9 |
