1L9K

dengue methyltransferase

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	RNA-DIRECTED RNA POLYMERASE	polymer	305	34397.0	1	UniProt (P12823)	Dengue virus	methyltransferase
2	B, C, D, E, F (A)	SULFATE ION	non-polymer		96.1	5	Chemie (SO4)
3	G (A)	S-ADENOSYL-L-HOMOCYSTEINE	non-polymer		384.4	1	Chemie (SAH) PubChem (16760024) PubChem (193) PubChem (25210495) PubChem (13792) PubChem (177678424) PubChem (44361184) PubChem (21125603) PubChem (46936206) PubChem (50989525) PubChem (25203782) PubChem (51380914) PubChem (52224398) PubChem (189149) PubChem (57544532) PubChem (439155) PubChem (59046843) PubChem (59170628) PubChem (59576228) PubChem (66805708) PubChem (70689219) PubChem (70702054) PubChem (70832431) PubChem (52224400) PubChem (5284331) PubChem (6419189) PubChem (118374891) PubChem (118560068) PubChem (71170554) PubChem (13231890) PubChem (164157219) PubChem (126969526) PubChem (129105892) PubChem (143518505) PubChem (154578335) PubChem (163054214) PubChem (163335525)
4	H (A)	water	water		18.0	65	Chemie (HOH)

Sequence modifications

A: 4 - 296 (UniProt: P12823)

PDB	External Database	Details
Met -8	-	expression tag
Arg -7	-	expression tag
Gly -6	-	expression tag
Ser -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag
His 1	-	expression tag
Gly 2	-	expression tag
Ser 3	-	expression tag
Ile 135	Val 2623	engineered mutation
Arg 139	Lys 2627	engineered mutation
Ser 173	Asn 2661	engineered mutation
Ser 188	Pro 2676	engineered mutation
Lys 193	Arg 2681	engineered mutation
Ala 196	Thr 2684	engineered mutation
His 201	Tyr 2689	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	34397.0
Non-Polymers*	Number of molecules	6
	Total formula weight	864.7
All*	Total formula weight	35261.8

*Water molecules are not included.