1L0X
TCR beta chain complexed with streptococcal superantigen SpeA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | 14.3.d T cell receptor beta chain | polymer | 238 | 26568.5 | 2 | UniProt (P01851) Pfam (PF07654) | Mus musculus (house mouse) | |
| 2 | B, D (B, D) | Exotoxin type A | polymer | 221 | 25803.9 | 2 | UniProt (P08095) Pfam (PF01123) Pfam (PF02876) UniProt (by SIFTS) (P0DJY7) | Streptococcus pyogenes | Scarlet fever toxin, Erythrogenic toxin, SPE A |
| 3 | E, F, G (B, D) | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
| 4 | H, I, J, K (A, B, C, D) | water | water | 18.0 | 181 | Chemie (HOH) |
Sequence modifications
A, C: 3 - 246 (UniProt: P01851)
B, D: 1 - 221 (UniProt: P08095)
| PDB | External Database | Details |
|---|---|---|
| Gln 24 | Asn 53 | engineered mutation |
| Gln 74 | Asn 102 | engineered mutation |
| - | Gln 125 | SEE REMARK 999 |
| Gly 99 | - | SEE REMARK 999 |
| Ser 100 | - | SEE REMARK 999 |
| Tyr 101 | - | SEE REMARK 999 |
| Gln 121 | Asn 146 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Ser 90 | Cys 120 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 104744.8 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 276.3 | |
| All* | Total formula weight | 105021.1 |
