1KY5
D244E mutant S-Adenosylhomocysteine hydrolase refined with noncrystallographic restraints
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | S-adenosylhomocysteine hydrolase | polymer | 431 | 47479.7 | 4 | UniProt (P10760) Pfam (PF05221) Pfam (PF00670) | Rattus norvegicus (Norway rat) | Adenosylhomocysteinase, AdoHcyase |
| 2 | E, G, I, K (A, B, C, D) | 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE | non-polymer | 665.4 | 4 | Chemie (NAI) PubChem (16219774) PubChem (928) PubChem (44119956) PubChem (44415182) PubChem (439153) PubChem (124934832) PubChem (126455899) PubChem (94865921) PubChem (94865923) PubChem (134693949) PubChem (12309339) PubChem (12309347) PubChem (124432988) PubChem (140875346) PubChem (11250888) PubChem (12309341) PubChem (124934831) PubChem (124934833) PubChem (162951601) PubChem (162951600) PubChem (164575491) PubChem (169545638) PubChem (170905224) PubChem (174316169) PubChem (129607000) PubChem (129628338) PubChem (146167236) PubChem (162951602) PubChem (174084875) | |||
| 3 | F, H, J, L (A, B, C, D) | 3'-OXO-ADENOSINE | non-polymer | 265.2 | 4 | Chemie (ADY) PubChem (17753822) PubChem (46936625) PubChem (446824) PubChem (4471889) | |||
| 4 | M, N, O, P (A, B, C, D) | water | water | 18.0 | 252 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 431 (UniProt: P10760)
| PDB | External Database | Details |
|---|---|---|
| Glu 244 | Asp 244 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 189919.0 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 3722.7 | |
| All* | Total formula weight | 193641.6 |
