1KTL

The human non-classical major histocompatibility complex molecule HLA-E

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C	HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, ALPHA CHAIN	polymer	274	31511.6	2	UniProt (P13747) Pfam (PF00129) Pfam (PF07654) In PDB	Homo sapiens (human)	HLA-E heavy chain; major histocompatibility complex, class I, E; HLA-E class I protein; ALPHA CHAIN OF MHC COMPLEX CLASS I
2	B, D	BETA-2-MICROGLOBULIN	polymer	100	11879.4	2	UniProt (P01884) Pfam (PF07654) UniProt (by SIFTS) (P61769) In PDB	Homo sapiens (human)	beta 2-microglobulin; BETA CHAIN OF MHC COMPLEX CLASS I
3	P, Q	Peptide VTAPRTLLL	polymer	9	984.2	2			peptide B27
4	A	SULFATE ION	non-polymer		96.1	1	Chemie (SO4)

Sequence modifications

A, C: 1 - 274 (UniProt: P13747)

PDB	External Database	Details
Gly 107	Arg 128	engineered mutation
Ala 256	Arg 277	conflict

B, D: 1 - 99 (UniProt: P01884)

PDB	External Database	Details
Met 1	-	cloning artifact

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	88750.3
Non-Polymers*	Number of molecules	1
	Total formula weight	96.1
All*	Total formula weight	88846.4

*Water molecules are not included.