1KTL
The human non-classical major histocompatibility complex molecule HLA-E
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, ALPHA CHAIN | polymer | 274 | 31511.6 | 2 | UniProt (P13747) Pfam (PF00129) Pfam (PF07654) | Homo sapiens (human) | HLA-E heavy chain; major histocompatibility complex, class I, E; HLA-E class I protein; ALPHA CHAIN OF MHC COMPLEX CLASS I |
| 2 | B, D (B, D) | BETA-2-MICROGLOBULIN | polymer | 100 | 11879.4 | 2 | UniProt (P01884) Pfam (PF07654) UniProt (by SIFTS) (P61769) | Homo sapiens (human) | beta 2-microglobulin; BETA CHAIN OF MHC COMPLEX CLASS I |
| 3 | E, F (P, Q) | Peptide VTAPRTLLL | polymer | 9 | 984.2 | 2 | peptide B27 | ||
| 4 | G (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) |
Sequence modifications
A, C: 1 - 274 (UniProt: P13747)
B, D: 1 - 99 (UniProt: P01884)
| PDB | External Database | Details |
|---|---|---|
| Gly 107 | Arg 128 | engineered mutation |
| Ala 256 | Arg 277 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Met 1 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 88750.3 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 96.1 | |
| All* | Total formula weight | 88846.4 |
