1KTL
The human non-classical major histocompatibility complex molecule HLA-E
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, C | HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, ALPHA CHAIN | polymer | 274 | 31511.6 | 2 | UniProt (P13747) Pfam (PF00129) Pfam (PF07654) In PDB | Homo sapiens (human) | HLA-E heavy chain; major histocompatibility complex, class I, E; HLA-E class I protein; ALPHA CHAIN OF MHC COMPLEX CLASS I |
2 | B, D | BETA-2-MICROGLOBULIN | polymer | 100 | 11879.4 | 2 | UniProt (P01884) Pfam (PF07654) UniProt (by SIFTS) (P61769) In PDB | Homo sapiens (human) | beta 2-microglobulin; BETA CHAIN OF MHC COMPLEX CLASS I |
3 | P, Q | Peptide VTAPRTLLL | polymer | 9 | 984.2 | 2 | peptide B27 | ||
4 | A | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) |
Sequence modifications
A, C: 1 - 274 (UniProt: P13747)
B, D: 1 - 99 (UniProt: P01884)
PDB | External Database | Details |
---|---|---|
Gly 107 | Arg 128 | engineered mutation |
Ala 256 | Arg 277 | conflict |
PDB | External Database | Details |
---|---|---|
Met 1 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 6 |
Total formula weight | 88750.3 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 96.1 | |
All* | Total formula weight | 88846.4 |