1KSW
Structure of Human c-Src Tyrosine Kinase (Thr338Gly Mutant) in Complex with N6-benzyl ADP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC | polymer | 452 | 51665.5 | 1 | UniProt (P12931) Pfam (PF00018) Pfam (PF00017) Pfam (PF07714) | Homo sapiens (human) | C-SRC |
| 2 | B (A) | N6-BENZYL ADENOSINE-5'-DIPHOSPHATE | non-polymer | 517.3 | 1 | Chemie (NBS) | |||
| 3 | C (A) | water | water | 18.0 | 46 | Chemie (HOH) |
Sequence modifications
A: 83 - 533 (UniProt: P12931)
| PDB | External Database | Details |
|---|---|---|
| Met 82 | - | initiating methionine |
| Gly 338 | Thr 340 | engineered mutation |
| Ptr 527 | Tyr 529 | modified residue |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 51665.5 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 517.3 | |
| All* | Total formula weight | 52182.8 |
