1KMQ
Crystal Structure of a Constitutively Activated RhoA Mutant (Q63L)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | TRANSFORMING PROTEIN RHOA | polymer | 184 | 20646.6 | 1 | UniProt (P61586) Pfam (PF00071) | Homo sapiens (human) | H12 |
| 2 | B, C (A) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 3 | D (A) | PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER | non-polymer | 522.2 | 1 | Chemie (GNP) | |||
| 4 | E, F (A) | 1,4-DIETHYLENE DIOXIDE | non-polymer | 88.1 | 2 | Chemie (DIO) | |||
| 5 | G (A) | water | water | 18.0 | 210 | Chemie (HOH) |
Sequence modifications
A: 4 - 181 (UniProt: P61586)
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | cloning artifact |
| Ala -1 | - | cloning artifact |
| Met 0 | - | cloning artifact |
| Gly 1 | - | cloning artifact |
| Ser 2 | - | cloning artifact |
| Pro 3 | - | cloning artifact |
| Asn 25 | Phe 25 | engineered mutation |
| Leu 63 | Gln 63 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 20646.6 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 747.0 | |
| All* | Total formula weight | 21393.7 |
