1KLU
Crystal structure of HLA-DR1/TPI(23-37) complexed with staphylococcal enterotoxin C3 variant 3B2 (SEC3-3B2)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DR ALPHA CHAIN | polymer | 179 | 20784.5 | 1 | UniProt (P01903) Pfam (PF00993) Pfam (PF07654) | Homo sapiens (human) | HLA-DR1 alpha subunit; hla-dr antigen alpha chain |
| 2 | B (B) | HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DR-1 BETA CHAIN | polymer | 190 | 22080.7 | 1 | UniProt (P04229) Pfam (PF00969) Pfam (PF07654) UniProt (by SIFTS) (P01911) | Homo sapiens (human) | HLA-DR1 beta subunit; HLA-DR beta 1 chain |
| 3 | C (C) | Triosephosphate isomerase peptide | polymer | 15 | 1469.7 | 1 | UniProt (by SIFTS) (P60174) | ||
| 4 | D (D) | ENTEROTOXIN TYPE C-3 | polymer | 239 | 27721.1 | 1 | UniProt (P0A0L5) Pfam (PF01123) Pfam (PF02876) | Staphylococcus aureus | enterotoxin C3; SEC3 |
| 5 | E, F, G, H (A, B, C, D) | water | water | 18.0 | 405 | Chemie (HOH) |
Sequence modifications
D: 1 - 239 (UniProt: P0A0L5)
| PDB | External Database | Details |
|---|---|---|
| Ser 43 | Lys 70 | engineered mutation |
| Phe 45 | Leu 72 | engineered mutation |
| Lys 46 | Ala 73 | engineered mutation |
| Trp 47 | His 74 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 72055.8 | |
| All* | Total formula weight | 72055.8 |
