1KL2

Crystal Structure of Serine Hydroxymethyltransferase Complexed with Glycine and 5-formyl tetrahydrofolate

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Serine Hydroxymethyltransferase	polymer	419	45711.7	2	UniProt (Q7SIB6) Pfam (PF00464)	Geobacillus stearothermophilus	SERINE METHYLASE, SHMT
2	C, F (A, B)	PYRIDOXAL-5'-PHOSPHATE	non-polymer		247.1	2	Chemie (PLP)
3	D, G (A, B)	GLYCINE	non-polymer		75.1	2	Chemie (GLY)
4	E, H (A, B)	N-{[4-({[(6R)-2-amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)phenyl]carbonyl}-L-glutamic acid	non-polymer		473.4	2	Chemie (FON)
5	I, J (A, B)	water	water		18.0	57	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	91423.5
Non-Polymers*	Number of molecules	6
	Total formula weight	1591.3
All*	Total formula weight	93014.8

*Water molecules are not included.