1KJ4
SUBSTRATE SHAPE DETERMINES SPECIFICITY OF RECOGNITION RECOGNITION FOR HIV-1 PROTEASE: ANALYSIS OF CRYSTAL STRUCTURES OF SIX SUBSTRATE COMPLEXES
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | POL polyprotein | polymer | 99 | 10800.8 | 4 | UniProt (P03369) Pfam (PF00077) | Human immunodeficiency virus 1 | |
| 2 | E, F (P, S) | gag polyprotein | polymer | 10 | 1161.3 | 2 | UniProt (P20875) | ||
| 3 | G, H, I, J, K... (A, B, C, D) | ACETATE ION | non-polymer | 59.0 | 12 | Chemie (ACT) PubChem (175) | |||
| 4 | S, T, U, V, W (A, B, C, D, S) | water | water | 18.0 | 43 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 99 (UniProt: P03369)
| PDB | External Database | Details |
|---|---|---|
| Lys 7 | Gln 63 | engineered mutation |
| Asn 25 | Asp 81 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 45525.6 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 708.5 | |
| All* | Total formula weight | 46234.2 |
