1KI6
CRYSTAL STRUCTURE OF THYMIDINE KINASE FROM HERPES SIMPLEX VIRUS TYPE I COMPLEXED WITH A 5-IODOURACIL ANHYDROHEXITOL NUCLEOSIDE
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | THYMIDINE KINASE | polymer | 331 | 35753.0 | 1 | UniProt (P03176) Pfam (PF00693) UniProt (by SIFTS) (P0DTH5) | Herpes simplex virus (type 1 / strain 17) | TK |
| 2 | B (B) | THYMIDINE KINASE | polymer | 331 | 35779.1 | 1 | UniProt (P03176) Pfam (PF00693) UniProt (by SIFTS) (P0DTH5) | Herpes simplex virus (type 1 / strain 17) | TK |
| 3 | C, E (A, B) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 4 | D, F (A, B) | 1',5'-ANHYDRO-2',3'-DIDEOXY-2'-(5-IODOURACIL-1-YL)-D-ABABINO-HEXITOL | non-polymer | 368.1 | 2 | Chemie (AHU) | |||
| 5 | G, H (A, B) | water | water | 18.0 | 275 | Chemie (HOH) |
Sequence modifications
A: 46 - 376 (UniProt: P03176)
| PDB | External Database | Details |
|---|---|---|
| Ala 280 | Pro 280 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 71532.1 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 928.4 | |
| All* | Total formula weight | 72460.5 |
