1KFV

Crystal Structure of Lactococcus lactis Formamido-pyrimidine DNA Glycosylase (alias Fpg or MutM) Non Covalently Bound to an AP Site Containing DNA.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C (D, G)	5'-D(*CP*TP*CP*TP*TP*TP*(PDI)P*TP*TP*TP*CP*TP*C)-3'	polymer	13	3683.4	2
2	B, D (E, H)	5'-D(*GP*AP*GP*AP*AP*AP*CP*AP*AP*AP*GP*AP*G)-3'	polymer	13	4066.7	2
3	E, F (A, B)	Formamido-pyrimidine DNA glycosylase	polymer	271	31263.7	2	UniProt (P42371) Pfam (PF01149) Pfam (PF06831) Pfam (PF06827)	Lactococcus lactis	FAPY-DNA glycosylase, FPG, MUTM
4	G, I (A, B)	ZINC ION	non-polymer		65.4	2	Chemie (ZN)
5	H, J (A, B)	GLYCEROL	non-polymer		92.1	2	Chemie (GOL)
6	K, L, M, N, O... (D, E, G, H, A...)	water	water		18.0	54	Chemie (HOH)

Sequence modifications

A, B: 1 - 271 (UniProt: P42371)

PDB	External Database	Details
Gly 1	Pro 2	engineered mutation
Mse 32	Met 33	modified residue
Mse 75	Met 76	modified residue
Mse 96	Met 97	modified residue
-	Asp 139	see remark 999
Mse 231	Met 233	modified residue

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	78027.6
Non-Polymers*	Number of molecules	4
	Total formula weight	315.0
All*	Total formula weight	78342.6

*Water molecules are not included.