1KAE
L-HISTIDINOL DEHYDROGENASE (HISD) STRUCTURE COMPLEXED WITH L-HISTIDINOL (SUBSTRATE), ZINC AND NAD (COFACTOR)
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Histidinol dehydrogenase | polymer | 434 | 46481.4 | 2 | UniProt (P06988) Pfam (PF00815) In PDB | Escherichia coli | HDH |
2 | A, B | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
3 | A, B | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
4 | A | 2,3-DIHYDROXY-1,4-DITHIOBUTANE | non-polymer | 154.3 | 1 | Chemie (DTT) | |||
5 | A | L-histidinol | non-polymer | 142.2 | 1 | Chemie (HSO) | |||
6 | A, B | NICOTINAMIDE-ADENINE-DINUCLEOTIDE | non-polymer | 663.4 | 2 | Chemie (NAD) | |||
7 | B | IMIDAZOLE | non-polymer | 69.1 | 1 | Chemie (IMD) | |||
8 | B | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
9 | water | water | 18.0 | 626 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 434 (UniProt: P06988)
PDB | External Database | Details |
---|---|---|
Mse 1 | Met 0 | modified residue |
Glu 15 | Val 14 | SEE REMARK 999 |
Mse 22 | Met 21 | modified residue |
Mse 88 | Met 87 | modified residue |
Mse 144 | Met 143 | modified residue |
Ser 150 | Arg 149 | SEE REMARK 999 |
Mse 232 | Met 231 | modified residue |
Mse 277 | Met 276 | modified residue |
Leu 313 | Ser 312 | SEE REMARK 999 |
Mse 390 | Met 389 | modified residue |
Leu 403 | Val 402 | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 92962.8 | |
Non-Polymers* | Number of molecules | 12 |
Total formula weight | 2299.5 | |
All* | Total formula weight | 95262.3 |