1K0Y
X-ray Crystallographic Analyses of Symmetrical Allosteric Effectors of Hemoglobin. Compounds Designed to Link Primary and Secondary Binding Sites
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C | hemoglobin alpha chain | polymer | 141 | 15150.4 | 2 | UniProt (P69905) Pfam (PF00042) In PDB | Homo sapiens (human) | |
| 2 | B, D | hemoglobin beta chain | polymer | 146 | 15890.2 | 2 | UniProt (P68871) Pfam (PF00042) In PDB | Homo sapiens (human) | |
| 3 | A, B, C, D | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 4 | Chemie (HEM) | |||
| 4 | B, D | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 5 | D | 2-{4-[(3{2-[4-(1-CARBOXY-1-METHYL-ETHOXY)-PHENYL]-ACETYLAMINO}-PHENYLCARBAMOYL)-METHYL]-PHENOXY}-2-METHYL-PROPIONIC ACID | non-polymer | 548.6 | 2 | Chemie (CNO) | |||
| 6 | water | water | 18.0 | 257 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 62081.1 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 3755.2 | |
| All* | Total formula weight | 65836.3 |
