1JWS
Crystal Structure of the Complex of the MHC Class II Molecule HLA-DR1 (HA peptide 306-318) with the Superantigen SEC3 Variant 3B1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | HLA class II histocompatibility antigen, DR alpha chain | polymer | 182 | 21155.9 | 1 | UniProt (P01903) Pfam (PF00993) Pfam (PF07654) | Homo sapiens (human) | |
| 2 | B (B) | HLA class II histocompatibility antigen, DR-1 beta chain | polymer | 190 | 22080.7 | 1 | UniProt (P04229) Pfam (PF00969) Pfam (PF07654) UniProt (by SIFTS) (P01911) | Homo sapiens (human) | |
| 3 | C (C) | HA peptide | polymer | 13 | 1506.8 | 1 | |||
| 4 | D (D) | Enterotoxin type C-3 | polymer | 239 | 27660.0 | 1 | UniProt (P0A0L5) Pfam (PF01123) Pfam (PF02876) | Staphylococcus aureus | SEC3 |
| 5 | E, F, G, H (A, B, C, D) | water | water | 18.0 | 141 | Chemie (HOH) |
Sequence modifications
D: 1 - 239 (UniProt: P0A0L5)
| PDB | External Database | Details |
|---|---|---|
| Gly 43 | Lys 70 | engineered mutation |
| Met 44 | Phe 71 | engineered mutation |
| Phe 45 | Leu 72 | engineered mutation |
| Asn 46 | Ala 73 | engineered mutation |
| Trp 47 | His 74 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 72403.4 | |
| All* | Total formula weight | 72403.4 |
