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1JVN

CRYSTAL STRUCTURE OF IMIDAZOLE GLYCEROL PHOSPHATE SYNTHASE: A TUNNEL THROUGH A (BETA/ALPHA)8 BARREL JOINS TWO ACTIVE SITES

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
BIFUNCTIONAL HISTIDINE BIOSYNTHESIS PROTEIN HISHFpolymer55561564.32UniProt (P33734)
Pfam (PF00117)
Pfam (PF00977)
Saccharomyces cerevisiae (baker's yeast)IMIDAZOLE GLYCEROPHOSPHATE SYNTHASE; GLUTAMINE AMIDOTRANSFERASE:CYCLASE; HIS7P; CYCLASE HIS7; AMIDOTRANSFERASE HIS7
2C, G
(A, B)
NICKEL (II) IONnon-polymer58.72Chemie (NI)
3D, E, F, H, I
(A, B)
SULFATE IONnon-polymer96.15Chemie (SO4)
4J
(B)
PYROPHOSPHATE 2-non-polymer176.01Chemie (POP)
5K, L
(A, B)
waterwater18.0412Chemie (HOH)
Sequence modifications
A, B: 1 - 552 (UniProt: P33734)
PDBExternal DatabaseDetails
Gly -3-expression tag
Ser -2-expression tag
His -1-expression tag
143 83Cys 83modified residue
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight123128.5
Non-Polymers*Number of molecules8
Total formula weight773.7
All*Total formula weight123902.2
*Water molecules are not included.

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PDB entries from 2025-12-10

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